Houghton Street Partners, in collaboration with Kingston International College, works with leading universities, research institutions and medical institutions to fund cutting-edge research with the potential to significantly advance the frontiers of human knowledge and help solve humanity’s most pressing problems.
Houghton Street Partners has identified cancer research as a key focus area and currently partners with Imperial College and the Royal Brompton Hospital - Europe’s leading heart and lung hospital – in London to fund potentially groundbreaking approaches to early cancer detection and treatment. They are led by Dr. Eric Lim, Consultant Thoracic Surgeon at The Royal Brompton Hospital and Clinical Senior Lecturer at Imperial College, London.
Ex-vivo cellular assessment of chemo-sensitivity in lung cancer This research project focuses on personalised medicine by developing cell-based models to predict an individual's tumour sensitivity to chemotherapeutic agents.+
Antibody-independent micro filtration biochip for the diagnosis of lung cancer This research project focuses on the detection of circulating tumour cells (CTCs) using an antibody-independent microfluidic filtration system to filter peripheral blood and trap CTCs. To date, research results have been presented at the British Toracic Oncology Group Meeting 2011, the World Circulating Tumour Cells Conference 2011 and the IASLC symposium in London.+
Antibody Independent Microfluidic Cell Capture of Circulating Tumour Cells for Diagnosis of Cancer This research project is a continuation of the antibody-independent micro filtration biochip for the diagnosis of lung cancer project.+
Non-invasive KRAS and EFGR mutation testing of primary lung cancer via peripheral blood circulating tumour cells This research project focuses on predicting the underlying mutation status of the primary tumour through capture and real-time polymerase chain reaction (PT-PCR) of circulating tumour cells (CTC) DNA.+
he ability of a filter-based antibody-independent approach to capture circulating tumour cells for the diagnosis of lung cancer This research explores the performance of filtration-based technology using cytomorphologic criteria in patients undergoing surgery for lung cancer.+
The utility of peripheral blood circulating tumour cells for the detection of Kras, EGFR and BRAF mutations in Primary lung cancer This research determines the utility of DNA extracted from CTCs to screen for the underlying primary tumour mutation+